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The administration of Cu(II) was shown to stimulate the release of GnRH from isolated hypothalamic granules and median eminence explants, and increases levels of GnRH in the pituitary stalk of rabbits

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[DOI] [PMC free article] [PubMed] [Google Scholar] 178.Saha S.K., Lee S.B., Won J., Choi H.Y., Kim K., Yang G.M., Dayem A.A., Cho S.G