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Caffeine "Heart palpitations are a potential concern with supplements containing green tea, guarana, yerba mate, or kola nut — all ingredients that naturally contain caffeine," says Tod Cooperman, MD, the president of ConsumerLab, an independent testing company in White Plains, New York, focused on health and nutrition products

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It is also used for heart disease, premenstrual syndrome (PMS), depression, morning sickness, Alzheimer disease, menstrual cramps, diabetes, and many other conditions, but there is no good scientific evidence to support many of these other uses