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Sufficient carotenoid intake (zeaxanthin, lutein, β -cryptoxanthin, α -carotene, β -carotene, total carotenes, total xanthophylls, and total carotenoids) is considered to protect against age-related diseases by altering thioredoxin-interacting protein DNA methylation status in men [237]

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These agents promote the proliferation of beneficial bacteria, while suppressing harmful strains ( Table 2 ) 178 , 179