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Moreover, N-acetylcysteine, angiotensin-converting enzyme inhibitors, catalase, mannitol, superoxide dismutase, and vitamin E have been shown to have antioxidant properties that help to prevent I-R injury [158]

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In addition, GSH has been shown to regulate nitric oxide homeostasis (Hogg, 2002), modulate the activity of proteins by post-translational modification (protein S-glutathionylation) (Pompella et al., 2003), and modulate the activity of neurotransmitter receptors (Oja et al., 2000)