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Activation of noncanonical Wnt signalling enhances Aβ production, while activation of canonical Wnt signalling suppresses Aβ production

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These MSC-microbiome interactions markedly augmented transcription of immunomodulatory genes including COX2, IL-6, and IL-8 and upregulated secretion of prostaglandin E2 (PGE2), IL-6, and IL-8 [126]