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Nitric-oxide (L-arginine–NO) system BPC-157 has been characterized in animal models as a modulator of the NO pathway, with reported interactions with both L-NAME (NO-synthase inhibition) and L-arginine (NO-synthase substrate) co-administration paradigms (Seiwerth et al., 2014)

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01Mechanism of action BPC-157 — Cytoprotective pentadecapeptide (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) BPC-157 is a 15-amino-acid fragment of a larger 40 kDa protein isolated from human gastric juice