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During VSV and IAV infection, neutrophil-derived itaconate alkylates key cysteines on the Rab GDP-dissociation inhibitor GDI2 (Cys203, Cys335, Cys414), blocking recycling of Rab GTPases from membranes to the cytosol, which enhances membrane retention of Rabs and facilitates viral trafficking and replication

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[DOI] [PMC free article] [PubMed] [Google Scholar] Silverman A

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