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For instance, single-cell RNA sequencing analysis have revealed that cGAS-STING pathway serves a unique role in maintaining the antitumor functions of CD8+ T cells (23), suggesting that different immune cells may differentially regulate DNA damage response (DDR) pathways through mechanisms such as epigenetic reprogramming

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2 Tretinoin is an active vitamin A derivative that binds to retinoic acid receptors and activates genes that control cell differentiation, proliferation, and collagen production

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