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10.1097/00001756-199702100-00040 [DOI] [PubMed] [Google Scholar] Mora F, Segovia G, del Arco A (2007) Aging, plasticity and environmental enrichment: structural changes and neurotransmitter dynamics in several areas of the brain

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Apoptotic cell death, adverse external environments, and the limited regenerative capacity of neurons all contribute to the central nervous system (CNS) inability to recover from traumatic brain injury (TBI) and the effect is multi-fold when exposed to PQQ (Zhang et al., 2012)