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Blood 118(21):182, 2011

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AD is characterized by a progressive reduction in the num ber and maturation of adult neurons in the dentate gyrus (DG) of the hippocampus (Moreno-Jimenez et al., 2019), suggesting an impairment in hippocampal neurogenesis that is closely correlated with the loss of hippocampal functions and cognitive decline (Hollands et al., 2017