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People who should be especially cautious include those with a history of eating disorders (the variable appetite effects could be destabilizing), those taking medications with narrow therapeutic windows (unpredictable tirzepatide blood levels could affect interactions), and those with GI conditions that might be worsened by daily GLP-1 agonist exposure

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Additional conclusive evidence for the action of TyrBm on HQ lies in the formation of brown crystals soaked in HQ that indicate on substrate oxidation as was previously shown by Sendovski et al