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Researcher synthesised demethoxycurcumin and bis-demethoxycurcumin, in HERr2 + cells and MCF-7, the phytochemicals were discovered to limit cancer cell proliferation, as shown by an IC50 value below 10 μM ( in vitro IC 50 concentrations may not directly reflect clinically achievable plasma or tissue levels, and translational interpretation requires pharmacokinetic validation

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This evidence reveals that the intact ETC with normal function is essential for ATP production in mitochondria and for the metabolism of energy substrates