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In fact, although most trials across different cancer types have been restricted to c-MET overexpressing tumors identified by different techniques (i.e., immunohistochemistry or FISH), the diagnostic tests and molecular predictive biomarkers to identify patients who may benefit from c-MET inhibition are still not well understood

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These results suggest that the decline in glutathione in neurons is more critical for the brain atrophy than that in astrocytes