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A 2013 paper in Endocrinology used a GHRH-receptor-targeted botulinum-neurotoxin construct to characterise pulsatile GH secretion mechanisms further (PMID 23825127), broadening the receptor-mechanism understanding

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Q: If PBM is used to treat an eye with early dry AMD and 20/20 BCVA, is this on-label or off-label use