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Phase I metabolism of dihexa, which was determined using pooled male rat liver microsomes, was found to be very low, with an average intrinsic clearance (Cl int ) of 2.72 µ l/min/mg and an average half-life of 509.4 minutes

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A 2022 study confirmed that compounds restoring follicular beta-catenin signaling produce measurable regrowth in androgenetic alopecia models (PMC 9693075)